An introduction to clinical problems associated with splenomegaly and hyposplenism. There is a case study involving a patient with severe anemia associated with splenic enlargement, and a description of the "Big Spleen Syndrome". MCQs help to consolidate your concepts of splenic function. ALL physicians should be able to: 1. list the important causes of splenomegaly 2. describe possible effects on the blood 3. demonstrate a systematic approach to diagnosis of the cause and suggest appropriate investigations and 4. describe the clinical effects of massive splenomegaly.
Author(s): Peter R. Galbraith MD, FRCP(C)
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